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Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury
Source: Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury
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Barclay Morrison III, associate professor of biomedical engineering at Columbia Engineering, has led the first study to determine underlying biological mechanisms that promote functional recovery of the blood-brain barrier (BBB) after blast injury. The research demonstrates that treatment with the glucocorticoid, dexamethasone, after primary blast injury promotes rapid recovery of an in vitro model of the BBB, a highly restrictive semi-permeable barrier whose primary function is to maintain the brain's microenvironment and protect it from potentially toxic substances.Source: Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury
