Eman said:
100% sure AJ this is why I have been so baffled. That was my thought to that that it is just holding better since heated. Then again after i heated and shook it made it alot clearer than it would normally be (not as many powder particles floating) so when it didnt separate back out like it normally should it worried me that something bad had happened since this is the first time iv ever had to do this to a oral. So you thing possibly some of the powder had melted and is just holding alot better since it was heated which is why there would be less particles floating.. Just wouldnt think a 10 sec nuke would do that. I mean it was a little warm but not even close to hot.
Your oral is perfectly fine. Sometimes when I produce a batch of suspension-orals, I blend them too much and or depending on the hormone, it comes too finely ground. The powder can get TOO fine if blended too much, and it will settle very tightly at the bottom. Microwaving for ten seconds is perfect, as it wont melt a plastic bottle (I dont know if this is my product or another vendors, I'm just speaking generally), and is enough to lower the viscosity of the liquid enough to help it mix easier when you shake it.
As for why there is less powder in the bottom, my answer is this: It's more than likely because some of the hormone was close to dissolving in the solution initially, but needed some heat to actually get it into solution. Once you heated it, some of the hormone is now dissolved, and some of the hormone is left suspended. You just turned a suspension into a suspension/solution blend. Nothing to worry about at all, unless you get it really cold again. Keep it room temperature or above 60 and you have nothing to worry about. If anything, this is slightly better than just having suspension as it will be a small % more accurate when you draw your doses.
Shaking the suspension, then immediately drawing your dose within seconds makes for EXTREMELY accurate doses. However, if you let something sit for 10...20...30...60 seconds after shaking, before drawing your dose, you could lose accuracy depending on the viscosity of the suspension (how thick it is). Less viscous suspensions require faster draw times, and thicker suspensions are more forgiving.
Hope this helps!
-Erik