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OK...we all do steroids. And we all know there are side effects to steroid use. With long-term use of high dose anabolic steroids there is an increased risk of liver damage or developing liver cancer. Life-threatening complications are also seen in the body by the use of anabolic steroids, and the most affected risk is associated with liver damage. Damage to the liver is evident when enzymes called aminotransferases to leak out of damaged liver cells into your bloodstream. Liver damage from anabolic steroids can also cause a condition called cholestasis. With this condition, bile, a digestive fluid made in liver and leaks out into the blood. Symptoms like itching, nausea, loss of appetite, dark urine and jaundice etc. So...how can we continue to use anabolics, and at the same time protect the liver? Let's examine a few things:
Only specific steroids can damage the liver i.e. alkylated steroids can give bad impact on liver function. Alkylated steroids are oral steroids that are:
1.not able to eliminate toxins present in liver without letting them get in the blood
2.avoid breakdown of toxins into the liver
3.inhibits the excretory function of liver.
Oral steroids are C17-Alpha Alkylated (C17-aa), which refers to a structural change in the hormone at the 17th carbon position. The reason for this modification is to help the drugs survive the first pass through the liver, where they can enter your system and provide benefits. But the downside is that the C17-aa modification also makes oral steroids toxic to the liver and is not able to eliminate toxins. Due to the liver toxicity, oral steroid usage should be limited to a maximum of 8 weeks. But the liver is a recover organ that’s able to heal and rejuvenate itself. It does not mean that you should over-excited and do not take responsibility to protect your organs.
The severity of side-effects of oral steroids and other drugs simultaneously increased the risk of liver and makes them more hepatotoxic. This might be associated with fatty liver disease, hepatic tumours, chronic vascular injury, and acute cholestatic syndrome. These changes occur in the liver might be life-threatening or recoverable.
1. USE NON-ALKYLATED STEROIDS
The chemical substitution occurring in testosterone occurring in the body in two forms are the 17-beta-esterification and the 17-alpha-alkylation. Testosterone is metabolized rapidly in the body; the esterification of the 17-beta-hydroxyl group makes the molecule more hydrophobic. The 17-alpha- alkylation induces the inhibition of metabolic deactivation by oxidation of the 17-beta hydroxy group in the liver, thus 17alpha-alkylated androgens can be effectively administered orally. Often the alkylation of the C-17 position of testosterone alters the relative anabolic potency about the masculinizing effects (androgenic steroids). The most used oral anabolic steroids are mesterolone, methandienone, methenolone, methandrostenolone, methyl testosterone, oxandrolone, stanozolol. The oral forms are resistant to immediate degradation and hepatotoxic.
Use non-alkylated injectable steroid as a base if you want free from liver susceptible effects. The injectable agents have undergone esterification of the 17-beta-hydroxy group to make them more soluble in lipids, leading to a slower release of the steroid into circulation. When these esters of testosterone i.e. testosterone enanthate, cypionate, and deaconate are administered in an oily suspension, they are released very slowly into the aqueous plasma because of their hydrophobicity. This extends their duration of action. Indeed, an important metabolic pathway of testosterone and its synthetic derivative is oxidation of the 17-beta-hydroxy group with the formation of the 17-keto metabolites. These polar metabolites are biologically inactive in the body. The injectable steroids are boldenone undecylenate, nandrolone decanoate, nandrolone phenpropionate, nandrolone undecanoate, testosterone cypionate, testosterone enanthate, testosterone propionate, trenbolone, trenbolone acetate, stanozolol.
The use of oral steroids alone is contraindicated. It puts a high pressure in the liver. If you want to keep your liver healthy, take a stack of an injectable with an oral. This would be beneficial for bulking as well as cutting. The dosage will not be higher than 350-750mg per week of stack and cycle duration would not be exceeded beyond six weeks.
2. TAKE SUPPLEMENTS TO PROTECT THE LIVER
You should supplement with a liver aid that provides all the building blocks needed to restore and repair your liver during and after oral steroid usage. If you use oral steroids in a responsible fashion, your liver enzyme levels will only slightly increase on cycle, and return to normal levels shortly after use is discontinued. Beyond supplementing with a liver aid during and after your cycle, you should also avoid any other activities that may be stressful to your liver, including some medications and excessive alcohol consumption.
3. UTILIZE SHORT CYCLES
Choose short steroid cycle over long cycles. Short duration cycle keeps the liver activity is still in normal condition and steroid influence is not devastating. High steroid dosage for a long time is too dangerous for your health risk. If you want to make your steroid cycle longer then replacing orals with the injectables is necessary. Use injectable steroid which carries the same effects as oral did and start your cycle with the 7th week.
4. TAKE BREAKS DURING CYCLING
Using more steroids continuously is not a productive method and leads to liver damage. The more steroids you take the higher resistance your body builds to it so that they become inefficient after a period of time. That’s why to take breaks and let the body detach from toxins that entered it during the time. Allow body time to get back in normal functioning. The liver has the property to regenerate itself if proper time is allowed. This property also works with other vital organs. After a while, you can get back in cycling.
Just remember...the liver is your body’s primary fat-burning organ, and it regulates important sex hormones such as testosterone. A healthy and well-functioning liver will make fat-loss and muscle-building goals much easier to achieve. The simplest things you can do to keep your liver healthy include: avoiding excessive alcohol consumption; following a healthy diet; getting regular exercise; and avoiding certain medications if possible. Before getting involved in any steroid cycle, make sure your liver function is normal.
Only specific steroids can damage the liver i.e. alkylated steroids can give bad impact on liver function. Alkylated steroids are oral steroids that are:
1.not able to eliminate toxins present in liver without letting them get in the blood
2.avoid breakdown of toxins into the liver
3.inhibits the excretory function of liver.
Oral steroids are C17-Alpha Alkylated (C17-aa), which refers to a structural change in the hormone at the 17th carbon position. The reason for this modification is to help the drugs survive the first pass through the liver, where they can enter your system and provide benefits. But the downside is that the C17-aa modification also makes oral steroids toxic to the liver and is not able to eliminate toxins. Due to the liver toxicity, oral steroid usage should be limited to a maximum of 8 weeks. But the liver is a recover organ that’s able to heal and rejuvenate itself. It does not mean that you should over-excited and do not take responsibility to protect your organs.
The severity of side-effects of oral steroids and other drugs simultaneously increased the risk of liver and makes them more hepatotoxic. This might be associated with fatty liver disease, hepatic tumours, chronic vascular injury, and acute cholestatic syndrome. These changes occur in the liver might be life-threatening or recoverable.
1. USE NON-ALKYLATED STEROIDS
The chemical substitution occurring in testosterone occurring in the body in two forms are the 17-beta-esterification and the 17-alpha-alkylation. Testosterone is metabolized rapidly in the body; the esterification of the 17-beta-hydroxyl group makes the molecule more hydrophobic. The 17-alpha- alkylation induces the inhibition of metabolic deactivation by oxidation of the 17-beta hydroxy group in the liver, thus 17alpha-alkylated androgens can be effectively administered orally. Often the alkylation of the C-17 position of testosterone alters the relative anabolic potency about the masculinizing effects (androgenic steroids). The most used oral anabolic steroids are mesterolone, methandienone, methenolone, methandrostenolone, methyl testosterone, oxandrolone, stanozolol. The oral forms are resistant to immediate degradation and hepatotoxic.
Use non-alkylated injectable steroid as a base if you want free from liver susceptible effects. The injectable agents have undergone esterification of the 17-beta-hydroxy group to make them more soluble in lipids, leading to a slower release of the steroid into circulation. When these esters of testosterone i.e. testosterone enanthate, cypionate, and deaconate are administered in an oily suspension, they are released very slowly into the aqueous plasma because of their hydrophobicity. This extends their duration of action. Indeed, an important metabolic pathway of testosterone and its synthetic derivative is oxidation of the 17-beta-hydroxy group with the formation of the 17-keto metabolites. These polar metabolites are biologically inactive in the body. The injectable steroids are boldenone undecylenate, nandrolone decanoate, nandrolone phenpropionate, nandrolone undecanoate, testosterone cypionate, testosterone enanthate, testosterone propionate, trenbolone, trenbolone acetate, stanozolol.
The use of oral steroids alone is contraindicated. It puts a high pressure in the liver. If you want to keep your liver healthy, take a stack of an injectable with an oral. This would be beneficial for bulking as well as cutting. The dosage will not be higher than 350-750mg per week of stack and cycle duration would not be exceeded beyond six weeks.
2. TAKE SUPPLEMENTS TO PROTECT THE LIVER
You should supplement with a liver aid that provides all the building blocks needed to restore and repair your liver during and after oral steroid usage. If you use oral steroids in a responsible fashion, your liver enzyme levels will only slightly increase on cycle, and return to normal levels shortly after use is discontinued. Beyond supplementing with a liver aid during and after your cycle, you should also avoid any other activities that may be stressful to your liver, including some medications and excessive alcohol consumption.
3. UTILIZE SHORT CYCLES
Choose short steroid cycle over long cycles. Short duration cycle keeps the liver activity is still in normal condition and steroid influence is not devastating. High steroid dosage for a long time is too dangerous for your health risk. If you want to make your steroid cycle longer then replacing orals with the injectables is necessary. Use injectable steroid which carries the same effects as oral did and start your cycle with the 7th week.
4. TAKE BREAKS DURING CYCLING
Using more steroids continuously is not a productive method and leads to liver damage. The more steroids you take the higher resistance your body builds to it so that they become inefficient after a period of time. That’s why to take breaks and let the body detach from toxins that entered it during the time. Allow body time to get back in normal functioning. The liver has the property to regenerate itself if proper time is allowed. This property also works with other vital organs. After a while, you can get back in cycling.
Just remember...the liver is your body’s primary fat-burning organ, and it regulates important sex hormones such as testosterone. A healthy and well-functioning liver will make fat-loss and muscle-building goals much easier to achieve. The simplest things you can do to keep your liver healthy include: avoiding excessive alcohol consumption; following a healthy diet; getting regular exercise; and avoiding certain medications if possible. Before getting involved in any steroid cycle, make sure your liver function is normal.
