TUDCA and NAC
One of TUDCA’s potential benefits is within your cells’ mitochondria. These are the energy generators in your cells. However, they do much more than creating energy or ATP.
Mitochondria are also involved in your cells’ metabolism and the maintenance of your cell membranes. They may even help defend your cells from viruses. (5)
These vital functions can strain your mitochondria. When they are too stressed and start to malfunction, they either trigger cell death (apoptosis) or mutate.
Too many cells dying before their appropriate time can lead to disease. On the flip side, if damaged cells don’t die, it can lead to conditions such as cancer. Neither option is good.
TUDCA supports your mitochondria and helps combat cell stress. It neutralizes free radicals to help your mitochondria function normally. (6)
Another component of your cells that can get overly stressed is the endoplasmic reticulum. This is like a manufacturing and packaging factory for your cells.
An excessive workload strains your cells’ endoplasmic reticulum and contributes to damage. That may trigger cell death to prevent dysfunction. (7)
Endoplasmic reticulum stress is linked to several conditions, including: (8)
Diabetes
Viral infections
Neurological conditions, including Alzheimer's disease
Cancer
TUDCA supports your endoplasmic reticulum to help prevent cells from mutating or dying prematurely.
As impressive as TUDCA is by itself, it pairs well with N-acetyl-cysteine (NAC). Your body uses NAC to make glutathione, one of your body’s most potent antioxidants.
The combination of TUDCA and NAC may improve their ability to squelch free radicals and lower inflammation, according to animal research. (9)
NAC is also a star player in its own right. It’s long been used to help protect the liver against toxins.